Listar por autor "López, Eduardo"
Mostrando ítems 1-6 de 6
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Exon-skipping brain natriuretic peptide variant is overexpressed in failing myocardium and attenuates brain natriuretic peptide production in vitro
Torrado, Mario; Iglesias Reinoso, Raquel; Centeno, Alberto; López, Eduardo; Mikhailov, Alexander T. (SAPE / Society for Experimental Biology and Medicine, 2010)[Abstract] Brain natriuretic peptide/natriuretic peptide precursor B (NPPB) is one of the most studied genes in relation to heart failure (HF) conditions. However, it is still unclear as to whether alternative splicing ... -
In vivo forced expression of myocardin in ventricular myocardium transiently impairs systolic performance in early neonatal pig heart
Torrado, Mario; Centeno, Alberto; López, Eduardo; Mikhailov, Alexander T. (UPV/EHU Press, 2008-01-30)[Abstract] The aim of this study was to determine the effects of forced expression of myocd-A in the left ventricular (LV) myocardium on cardiac performance in early neonatal piglets. LV transfection with the gene for ... -
Intron retention generates ANKRD1 splice variants that are co-regulated with the main transcript in normal and failing myocardium
Torrado, Mario; Iglesias, Raquel; Nespereira, Beatriz; Centeno, Alberto; López, Eduardo; Mikhailov, Alexander T. (Elsevier, 2009-03-31)[Abstract] The cardiac ankyrin repeat domain 1 protein (ANKRD1, also known as CARP) has been extensively characterized with regard to its proposed functions as a cardio-enriched transcriptional co-factor and stress-inducible ... -
Quantitative analysis of soft-bottom polychaetes of the Bellingshausen Sea and Gerlache Strait (Antarctica)
Parapar, Julio; López, Eduardo; Gambi, Maria Cristina; Núñez, Jorge; Ramos, Ana (Springer, 2011)The basin off the Bellingshausen Sea, in contrast to other better known areas such as the Antarctic Peninsula and the Ross and Weddell Seas, has been little investigated due to remoteness and the prevalence of ice for most ... -
Targeted gene-silencing reveals the functional significance of myocardin signaling in the failing heart
Torrado, Mario; Iglesias Reinoso, Raquel; Centeno, Alberto; López, Eduardo; Mikhailov, Alexander T. (PLoS, 2011)[Abstract] Background. Myocardin (MYOCD), a potent transcriptional coactivator of smooth muscle (SM) and cardiac genes, is upregulated in failing myocardium in animal models and human end-stage heart failure (HF). However, ... -
Updating the National Baseline of Non-Indigenous Species in Spanish Marine Waters
Png-González, Lydia; Comas-González, Robert; Calvo-Manazza, Matías; Follana-Berná, Guillermo; Ballesteros, Enric; Díaz-Tapia, P.; Falcón, Jesús M.; García Raso, José Enrique; Gofas, Serge Salvator; González-Porto, M.; López, Eduardo; Ramos Esplá, Alfonso; Velasco, Eva; Carbonell, Ana (MDPI, 2023-05-05)[Abstract] The introduction of new non-indigenous species (NIS) in Spanish marine waters is addressed under Descriptor 2 of the European Union’s Marine Strategy Framework Directive. National baseline inventories of NIS ...